- The development of the analysis system of hereditary respiratory diseases based on the next-generation sequencing
- The development of the analysis system of hereditary oncological diseases based on the next-generation sequencing
- The development of the software package that allows forecasting the effect of mutations on the structural and functional protein properties.
Laboratory for Sequencing and Mathematical Modeling of the Transcriptome
The main project of the laboratory is the development of the system for the diagnostics of rare Mendelian disorders with a usage of the massive parallel sequencing technologies
Sergey Kovalenko

Head of laboratory
Education
Associate professor
PhD in biology
Professional experience
Kamil Khafizov

Researcher
Professional experience
Artem Kasianov

Researcher
Professional experience
Olga Glazova

Junior researcher
Professional experience
Lev Petrenko
Senior researcher
Education
Academic Interests
Alina Matsvai
Laboratory assistant
Education
Academic Interests
Inna Kichatova
Laboratory assistant
Education
Kichatova holds a degree in medical biophysics from Volgograd State Medical University.
She also has a diploma of a laboratory geneticist from the Russian Medical Academy of Postgraduate Education.
Academic Interests
Maxim Ivanov
Technician
Education
Academic Interests
2013
Journal of Structural and Functional Genomics
Crystal structure of human Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2
Soniat M, Khafizov K
Moscow Institute of Physics and Technology
PLoS ONE
Alignment of helical membrane protein sequences using AlignMe
Stamm M, Staritzbichler R, Khafizov K, Forrest LR
Moscow Institute of Physics and Technology
The Breast
BRCA1 gene mutations frequency estimation by allele-specific real-time PCR of pooled genomic DNA samples
M. S. Anisimenko, D. V. Mitrofanov, O. B. Chasovnikova, M. I. Voevoda, S.P. Kovalenko
Moscow Institute of Physics and Technology
2014
Molecular Vision
Gene regulation by PAX6: Structural-functional correlations of missense mutants and transcriptional control of Trpm3/miR-204
Q. Xie, D. Ung, K. Khafizov, A. Fiser, A. Cvekl
Moscow Institute of Physics and Technology
Proceedings of the National Academy of Sciences
Trends in structural coverage of the protein universe and the impact of the Protein Structure Initiative
K. Khafizov, C. Madrid-Aliste , S.C. Almo , A. Fiser
Moscow Institute of Physics and Technology
Nucleic Acids Research
AlignMe – a Membrane Protein Sequence Alignment Web Server
M. Stamm, R. Staritzbichler, K. Khafizov, L.R. Forrest
Moscow Institute of Physics and Technology
Melanoma Research
Allele-specific RealTime PCR assay for sensitive detection of BRAF V600E mutation in melanoma samples
Shamanin V.A., Pisareva E.E., Gutkina N.I., Lyubchenko L.N., Schneider-Stock R., Kovalenko S.P.
Moscow Institute of Physics and Technology